Competency Questions for the Critical Path Ontology (CPONT) and KG

Please check off each item as the knowledge graph/SPARQL queries have been created to sufficiently answer the competency questions below:

• What are the differences in assessment types given to people living with different diagnoses?

• Given a previously unknown disease can a novel candidate procedure/therapy be identified through similarity with known diseases?

• Which subjects have at least one lab range outside of normal range (LBNRIND ne "NORMAL”)? Counts? Proportions?

• Which diagnosis has the highest number of female participants? Male participants?

• Do any subjects have a missing confirmation of disease-of-interest diagnosis?

• Which study has the greatest number participants?

• Which study has the highest number of relationships (page rank)?

• Which disease node has the greatest number of edges?

• Which subjects have a neuromuscular diseases?

• How many subjects have tumor diagnoses?